Technical support for ebook readers

Some of the ebooks are providing on the web as specially digitalized format, that is with “.djvu” formate. plz don not confuse with this. just follow the instructions given below.

Description:

DjVu (pronounced "déjà vu") is a digital document format with advanced compression technology and high performance value. DjVu allows for the distribution on the Internet and on DVD of very high resolution images of scanned documents, digital documents, and photographs. DjVu viewers are available for the web browser, the desktop, and PDA devices.

This format have 29 format extensions.  to see the extensions just see this link.

Instructions:

1. Just DOWNLOAD the software (name is WinDjView-1.0.1-Setup.exe  file). this is 2.73MB file.
2. Install the file in your system. automatically the “.djvu” extesion files will be open in your system.
3. This is very secured system to store our digitalized copies.
4. All the best.

Ecology by Odum is good book for CSIR NET examination

Ecology by Odum

Book Description
The late Eugene Odum was a pioneer in systems ecology and is credited with bringing ecosystems into the mainstream public consciousness as well as into introductory college instruction.

FUNDAMENTALS OF ECOLOGY was first published in 1953 and was the vehicle Odum used to educate a wide audience about ecological science. This Fifth Edition of FUNDAMENTALS OF ECOLOGY is co-authored by Odum's protege Gary Barrett and represents the last academic text Odum produced.

The text retains its classic holistic approach to ecosystem science, but incorporates and integrates an evolutionary approach as well. In keeping with a greater temporal/spatial approach to ecology, new chapters in landscape ecology, regional ecology, and global ecology have been added building on the levels-of-organization hierarchy. Also, a final chapter entitled "Statistical Thinking for Students of Ecology" provides a quantitative synthesis to the field of statistics. Contemporary and engaging, this text brings clarity and specificity to the study of ecology in the twenty-first century.

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Introduction to Protein Structure by Branden & Tooze

Introduction to Protein Structure by Branden & Tooze

Publisher:* Garland Science
Number Of Pages:* 410
Publication Date:* 1999-01-01
ISBN-10 / ASIN:* 0815323050
ISBN-13 / EAN:* 9780815323051
Binding:* Paperback

Year: 1999

Product Description:
Introduction to Protein Structure gives an up-to-date account of the principles of protein structure, with examples of key proteins in their biological context generously illustrated in full colour to illuminate the structural principles described in the text. The first few chapters introduces the general principles of protein structure both for novices and for non-specialists needing a primer. Subsequent chapters use specific examples of proteins to show how they fulfil a wide variety of biological functions. The book ends with chapters on the experimental approach to determining and predicting protein structure, as well as engineering new proteins to modify their functions.

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First download the above link after click the below link. it explains every thing about "How to open the link".

Technical support plz click here

CSIR-UGC-NET (June 2010) Life Science Previous Paper

Few Questions from the paper (Based on Memory)

1. Which among the following is not a polymer?
a) rubber
b) cellulose
c) vinyl alcohol

2. Sky appears blue because of
a) scattering of light
b) composition of sunlight
c) a and b

3. Four times the square of a number is one more than three times the number. Find the
number
a) 4       b) –4           c) 1            d) -1

4. Three balloons are of the same size,one was filled with hydrogen,another with helium
and one with carbon dioxide. let F1, F2, F3 be the buoyant forces acting on them, then
which of following is correct
a. F1>F2>F3           b. F3>F2>F1           c. F2=F1>F3               d. F3=F2>F1

5. Microorganism mostly used for controlling insect population include 
a. Bacillus thuriengenesis        b. Agrobacterium tumefaciens        

6.  Evolution of Dinosaurs time?
a. 6.5 millions years ago
b. 600 million yrs ago
c. 6 billion years ago
d. 60 million yrs ago.

7. Incorrect transfusion of blood results in death of the patient due to
a) precipitation
b) agglutination of blood cells
c) kidney failure

8. If the sample taken from HIV patient serum blood sample, will detect in Western
blotting
a) viral antigens
b) viral particles
c) viral proteins-specific antibodies

9. The antibiotic which causes pre-chain termination in protein synthesis in E.coli
a) puromycin
b) chloramphenicol
c) tetracyclin
d) Streptomycin

10. A myopic person have astigmatism is correcting by using
a) spherical convex lens only
b) cylinderical and convex lens
c) concave and cylinderical lens
d) spheriacal concave lens only


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Do not forget to say Thanks for IAFS (Institute for Advanced Science)
Just post your comment to say thanks in this blog.

Schaum's Outline of Biochemistry (Ebook)

Fortunately for you, there's Schaum's Outlines. More than 40 million students have trusted Schaum's to help them succeed in the classroom and on exams. Schaum's is the key to faster learning and higher grades in every subject. Each Outline presents all the essential course information in an easy-to-follow, topic-by-topic format. You also get hundreds of examples, solved problems, and practice exercises to test your skills.

This Schaum's Outline gives you:
• Practice problems with full explanations that reinforce knowledge
• Coverage of the most up-to-date developments in your course field
• In-depth review of practices and applications

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Metabolic Tips: WHILE YOU READ BIOCHEMISTRY SCAN FOR THE FOLLOWING tips

1. Three compulsory lists that must be at your tips-

• Ketogenic and Glucogenic amino acids.
• Essential and Nonessential amino acids.
• Basic, Acidic, Sulphur containing amino acids.

2. Regulatory Enzymes of pathways e.g.

• Citrate synthesis in citric acid cycle.
• Phosphofructokinase in Glycolysis.
• Pyruvate dehydrogenase in Pyruvate Oxidation.
• Pyruvate Carboxykinase in Gluconeogenesis.
• Glycogen Synthase in Glycogenesis.
• Phosphorylase in Glycogenolysis.
• G6PD in PPP.  
• HMG CoA reductase in cholesterol synthesis.

3. Search for ATP estimates e.g.,

• 8 ATP’s per Glucose molecule in Glycolysis under aerobic conditions.
• 30 ATP’s per Pyruvate molecule entering citric acid cycle.
• 129 ATP’s per palmitate undergoing b-oxidation.

4. Look for regulatory molecules and feedback inhibitions e.g.,

• Glucose-6-phosphate inhibition on hexokinase.
• Citrate’s inhibitory effect on phosphofructokinase 1.
• Alanine’s inhibitory effect on Pyruvate kinase.
• Acetyl CoA’s inhibitory effect on Pyruvate dehydrogenase.
• Long chain acyl CoA’s inhibitory effect on Acetyl CoA carboxylase.

5. Look for subcellular organelles where the reactions specifically occur.

• Enzymes of citric acid cycle in mitochondrial matrix.
• Enzymes of Glycolysis in cytosol.
• Enzymes of pentose phosphate pathway in cytosol.
• Enzymes of denovo synthesis of fatty acids in cytosol.
• Enzymes of fatty acid oxidation in mitochondria.

6. Always have a clarity regarding precise role of various lipoproteins.

• HDL is cholesterol scavenger.
• Chylomicrons carry dietary cholesterol.
• VLDL are vehicles of transport of triacylglycerol from the liver to extrahepatic tissues.

7. Vitamins and their role as coenzymes e.g.,

• Thiamine in oxidative decarboxylation.
• Niacin in dehydrogenase reactions.
• Pantothenic acid in CoA.
• Pyridoxal phosphate in muscle phosphorylase.
• Biotin in carboxylase enzymes.
• Vitamin B12 to produce succinyl CoA.
• Folate in transfer of one-carbon units.

8. Products that accumulate in metabolic disorders e.g.,

• Homogenisate in urine of Alkaptonuria patients
• Phenyl acetyl glutamine in phenylketonuria.
• Xanthurenate in Vitamin B6 deficiency.
• Branched chain ketonuria in Mapple syrup urine disease.

9. Check for key enzymes responsible for Metabolic disorders e.g.,

• Glucose-6-phosphates in von Gierkes.
• Hepatic fructokinase in essential fructosuria.
• Galactose-1-phosphate uridyl transferase in Galactosemia.
• Cystathionine-b-synthase in homocystinuria.

10. Where NADH forms, where NADPH forms, where FADH₂ forms, where substrate level phosphorylation occurs e.g.,

• FADH₂ in succinate dehydrogenase in citric acid cycle.
• NADH in all degradative reactions.
• NADPH in all synthetic reactions.

CSIR NET life science syllabus 2010--II

Unit 2:  CELLULAR ORGANIZATION 
 
A.  Membrane structure and function:  Structure of model membrane, lipid bilayer   and membrane protein diffusion, osmosis,  ion channels, active transport, ion pumps,   mechanism of sorting and regulation of intracellular transport, electrical properties of  membranes.
B.  Structural organization and function of intracellular organelles: Cell wall, nucleus, mitochondria, Golgi bodies, lysosomes, endoplasmic reticulum, peroxisomes, plastids, vacuoles, chloroplast,  structure &  function of cytoskeleton and its role in  motility.
 
C. Organization of genes and chromosomes:  Operon, interrupted genes, gene families, structure of chromatin and chromosomes, unique and  repetitive DNA, heterochromatin, euchromatin, transposons.
 
D.  Cell division and cell cycle: Mitosis and meiosis, their regulation, steps in cell cycle, and control of cell cycle.
 
E.  Microbial Physiology:  Growth, yield and characteristics, strategies of cell division, stress response.
 

Reference Books:

(You can download this ebooks)

1. Cell and Molecular Biology by Carp

2. The Cell and Molecular Biology by M.Cooper

Robert Edwards wins 2010 Nobel Prize in medicine for IVF revolution

Robert Edwards of Britain won the 2010 Nobel Prize in medicine on Monday for the development of in-vitro fertilisation (IVF), a breakthrough that has helped millions of infertile couples have children. The 85-year-old Edwards started working on IVF, a technique in which egg cells are fertilised outside the body and implanted in the womb, already in 1950s. On July 25, 1978, Louise Brown in Britain became the first baby born through the groundbreaking procedure. The medicine award was the first of the 2010 Nobel Prizes to be announced in a week's time.

Nobel prize 2010 work

ROBERT EDWARDS Wins the Nobel Prize in Physiology or Medicine for Pioneering In Vitro Fertilization 2010

Edwards's work with Patrick Steptoe resulted in the first birth of a test-tube baby--Louise Brown in 1978

Robert Edwards has won the 2010 Nobel Prize in Physiology or Medicine for his work to develop in vitro fertilization (IVF), the Nobel committee announced Monday. The procedure allows a human egg to be fertilized outside of the body and then implanted in a woman's; it has been used as a treatment for infertility for more than three decades.
Edwards, a professor emeritus at the University of Cambridge, began research on the problem of infertility in the 1950s. The first "test-tube baby," Louise Brown, was born in 1978, an event that the Nobel expert panel called "a paradigm shift." Since then, approximately four million babies have been born worldwide via IVF, many of whom now have children of their own.

Some studies have investigated whether IVF children are at a higher risk for some diseases and malformations, but the Nobel committee asserted that IVF babies are just as healthy as those who are naturally conceived, in a press conference Monday morning held in Stockholm. And some of the rare diseases that have been seen in IVF children might be attributable to underlying fertility issues, related to older or defective eggs or sperm or other germ cell defects.

Members of the Nobel committee said that this year's prize was not intended as a statement on the ethics of human embryonic stem cell research, a field that has come under increasing scrutiny after a surprise ban on U.S. federal funding in August (which has been stayed during the appeals process). Supporters of embryonic stem cell research point out that many fertilized eggs created for IVF are left to languish in freezers, with little hope of adoption. These extra embryos could be put to better use, they argue, as new human embryonic stem cell lines. Critics of human embryonic stem cell research contend, however, that because creating stem cell lines destroys the embryo, the more ethical choice is to leave the IVF extras intact. In its earlier years, assisted reproductive technology (ART) itself was a subject of ethical debate, but it is now a generally accepted treatment for many of the estimated 10 present of couples who are unable to conceive a child naturally.
Since it was first awarded in 1901 the Nobel Prize in Physiology or Medicine has rarely been bestowed on an advance that has led to such a singular clinical application (last year's Nobel in physiology or medicine was awarded to Elizabeth Blackburn, Carol Greider and Jack Szostak for their work with telomeres and telomerase), and it has rarely been given for work in reproductive research.

Throughout his long career working on the problem of infertility, Edwards had many collaborators, including Patrick Steptoe, with whom he created the first fertilized human egg in the laboratory in 1968. Their work built off of previous research that had successfully fertilized rabbit eggs in vitro. In the process of translating the work to human eggs, Edwards made a series of crucial discoveries, including "how human eggs mature, how different hormones regulate their maturation and at what time point the eggs are susceptible to the fertilizing sperm," the committee explained in release.
Edwards, who is 85 and said to be in ill health, was not able to speak with the committee this morning before the announcement. Instead, the committee notified his wife, who was delighted to hear of the high honor and said she was sure her husband would be as well. It is unclear whether Edwards will be able to attend the December award ceremony in Stockholm.

The IVF research had not been predicted on an annual short list offered by Reuters for Nobel predictions. Edwards had, however, received the 2001 Lasker Award, a medical research prize that has often preceded a Nobel. A Swedish daily newspaper carried a long profile of Edwards Monday morning as their pick for the prize, but committee members were cagey about whether it would investigate a possible leak.

Schaum’s Outlines of Immunology

Based on material from 400-600 level Immunology courses, this concise and thorough review of modern concepts in molecular, cellular, and systemic immunology contains over two hundred detailed problems with step-by-step solutions. Taking a problem-solving approach, Schaum's Outline of Immunology is an excellent supplement to any systematic textbook of modern immunology, focusing on the basic tenets of immunology as applied to the dynamics of immune responses and their outcomes, and is perfect for pre-med students who need help in their required immunology courses, as well as for medical and veterinary students who want to update their knowledge

CSIR NET life science syllabus 2010--I

1. MOLECULES AND THEIR INTERACTION RELAVENT TO BIOLOGY 
 
A.  Structure of atoms, molecules and chemical bonds.
B. Composition, structure and function of biomolecules (carbohydrates, lipids,  proteins, nucleic acids and vitamins).
C. Stabilizing interactions (Van der Waals, electrostatic, hydrogen bonding,
hydrophobic interaction, etc.).
D. Principles of biophysical chemistry (pH, buffer, reaction kinetics,
thermodynamics, colligative properties).
E. Bioenergetics, glycolysis, oxidative phosphorylation, coupled reaction, group  transfer, biological energy transducers.
F. Principles of catalysis, enzymes and enzyme kinetics, enzyme regulation,
mechanism of enzyme catalysis, isozymes.
G. Conformation of proteins (Ramachandran plot, secondary, tertiary and quaternary  structure; domains;  motif and folds).
H. Conformation of nucleic acids (A-, B-, Z-,DNA), t-RNA, micro-RNA).
I. Stability of protein and nucleic acid structures.
J. Metabolism of carbohydrates, lipids, amino acids, nucleotides and vitamins.

Reference books:

(You can download this books)

1. Biochemistry, Styer

2.Fundamentals of Biochemistry, Voet , Voet & Pratt; Upgraded edition

3. Principles of Biochemistry, Lehninger, Nelson & Cox

4. Fundamentals of Biochemistry, J.L.Jain

5. Understanding of Enzymes, Palmer

6. Textbook of Biochemistry, West & Todd, Oxford press

7. Harper’s Biochemistry, Murray

8. Biochemistry by Mathew, 3/e

9. Biochemistry by Zuby (the password for the zuby book is "econiches")

10. Biochemistry quiz questions

The liver is an important organ in the human body…How?

The liver is an important organ in the human body. Aside from creating functional molecules and chemicals for the body, it also removes compounds that could possibly poison other organs. Understanding the liver's functions will help prevent liver ailments by learning how to eat better to protect the liver and avoid disease

The Facts
The liver is the biggest organ in the human body. It is found in the right upper section of the abdomen and extends to the top of the diaphragm. The top part is beneath the right lung, the left end is under the heart, the left bottom side is above the stomach, and the right bottom side is above the gall bladder and right kidney and is protected by the right rib cage. Its color is reddish brown and it has a smooth texture. It has four lobes. The liver is larger when the human body is in its infancy stage and reduces in size as the body grows older. It weighs in at 1.2 to 1.5 kg in the female body and 1.3 to 1.6 kg in the male body.

Function:
The liver's function in the human body is to help break down and distribute nutrients in food. Medicine and alcohol are also processed by the liver so that toxins can be removed. The liver produces many chemical compounds that help in various bodily functions, some of which are to help blood to clot, maintain the glucose level in blood by breaking down and transforming glucose into glycogen, and regulating levels of amino acids, the building blocks of protein.

Significance:
The human body cannot function without the liver since it is responsible for many of the processes that the body needs to survive. One major function of the liver is to treat everything that is ingested and produced by the body and turn it into useful chemicals that aid other organs in maintaining the human body's functions. Byproducts that are not needed by the body are turned into waste and excreted.

Considerations:
Medications and alcohol have a strong effect on the liver's health. A perfectly functioning liver means that all the organs in the human body will operate just as well. Alcohol abuse and prolonged intake of certain medications change the liver's metabolism and will affect its functions, possibly leading to liver diseases like cirrhosis, hepatitis, liver cancer or Wilson's disease.

Prevention:
Drink plenty of fresh water throughout the day to help the liver do its job. Add more fruits and vegetables to your diet and give your liver a rest from red meats and processed food. Eat only fresh food and avoid food that has been reheated more than once. The liver weeds out any bacteria ingested through food intake, and too much harmful bacteria may cause liver damage. Avoid excessive intake of alcohol or avoid it altogether to prevent damage to the liver.

Content of Biochemistry ebook

Title: Fundamentals of Biochemistry

Author: J.L. Jain, Sunjay Jain, Nitin Jain

CONTENTS  of the Books

Part I Prefatory
1. Introduction
2. Water : The Solvent of Life
3. pH and Buffers
4. The Atom and Chemical Bonds

Part II BioMolecules
5. Carbohydrates I – General Structure of Monosaccharides
6. Carbohydrates II – Properties of Monosaccharides
7. Carbohydrates III – Oligosaccharides
8. Carbohydrates IV – Polysaccharides
9. Proteins I – General Structure
10. Proteins II – Classification
11. Proteins III –General Properties
12. Lipids I – General Structure
13. Lipids II – Classification
14. Lipids III – Properties of Fats and Oils
15. Nucleic Acids
16. Enzymes I – Nomenclature and Classification
17. Enzyme II – Characteristics and 3-‘D’ Structure
18. Enzymes III – Mechanism of Enzyme Action

part III bioenergetics and metabolism
19. Metabolic Concepts
20. Bioenergetics
21. Glycolysis
22. Pyruvate Oxidation and Citric Acid Cycle
23. Electron Transport and Oxidative Phosphorylation
24. Oxidation of Fatty Acids
25. Biosynthesis of Lipids
26. Oxidation of Amino Acids
27. Biosynthesis of Amino Acids
28. Biosynthesis of Proteins
29. Protein Targeting and Degradation
30. Genetic code.

Part IV hormone biochemistry

31. Animal Hormones
32. Plant Hormones

 

Part V nutrition biochemistry
33. Fat-soluble Vitamins
34. Water-soluble Vitamins

Part VI Analytical biochemistry
35. Biochemical Techniques  

APPENDIX

INDEX of the Book

Answers

Author Index

Glossary

(Links will update soon)

Fundamentals of Biochemistry by JL Jain is one of the good book

Title : Fundamentals of Biochemistry

Author: J.L. Jain, Sunjay Jain, Nitin Jain

ISBN Code : 81-219-2453-7

Book Code: 04277G

Total Pages :1230

Published By: S. Chand & Company Ltd. .

Preface:

Biochemistry is a new branch of science which aims at  answering, in chemical language, questions such as ‘What  is the life made of ?’ and ‘How does it work ?’ Whereas the eye works at the gross level of visible objects, the microscope reaches down to the cellular level, exposing details of the various cell organelles, including nuclei and other particles. Biochemistry, however, works at a still finer level that cannot be accessed by the ultra-modern optical or phase-contrast microscopes. In other words, it operates at a molecular level and thus brings to light the hidden secrets of life. The rapid development and enormous expansion of every phase of biochemistry has not only markedly enriched our knowledge about the nature of life but has also made biochemistry the very language of life itself.

Realising the paramount importance of this discipline of science, degree courses in biochemistry are now offered in a good number of colleges and universities. But the students offering this subject at undergraduate level come as raw hand, as biochemistry is not taught to them at the school level. It is, in fact, to meet the requirements of such students that this book has been written. Besides, the book may also serve an useful purpose for higher studies.

The book contains the basic concept of biochemistry written in a manner suited to the broad spectrum of the college students. The matter has been lucidly presented, orderly arranged and profusely illustrated. References have been included at the end of each chapter in order to guide the reader to the classical and current literature. A few appendices are given at the end. These may, however, prove useful to the reader. Some illustrations have been adapted from standard texts, journals and research papers. The sources of all such figures have been duly acknowledged in their legends. The author feels greatly beholden to their authors and publishers.

At the outset, the senior author of the book welcomes his two sons, Dr. Sunjay Jain and Er. Nitin Jain who have joined me as coauthors of this text, a credit which would have been given earlier to them as they were helping in a latent way in the evolution of the book for the past many years.
Thirty two years have elapsed since one of us (JLJ) embarked on the intellectual journey of writing a textbook of Biochemistry. As Biochemistry is growing at a dazzling pace, each edition has been demanding in a different way. In this latest 6th edition, the book has been thoroughly revised, enlarged and updated with not even a single chapter left untouched. Besides, one new chapter Genetic Code has been interpolated to enhance the scope and utility of the book. Addition of two new appendices is an added charm of the book : one is ‘The Nobel Prizes’, the world’s most venerated awards and the other is an exhaustive and highly explanatory Glossary, containing about 1700 words, along with etymology of many of them. Above and over all, this time the book has been presented in multicolour edition with profuse colour illustrations so as to increase its clarity, understand ability and legibility, especially of the diagrams.

It is hoped that the present book, in its revised and enlarged multicolour form, would serve in a still better way, the authors are keenly desirous of.
Gratitude is expressed to the students and teachers, both from India and abroad, who have sent in their valuable suggestions which have been given due consideration.

Healthy criticism and suggestions for further improvement of the book are solicited.

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